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Nolvadex is used to treat breast cancer that has spread to other sites in the body.

Use Nolvadex as directed by your doctor.

• Nolvadex may be taken by mouth with or without food.
• Take Nolvadex with water or other nonalcoholic fluids.
• Swallow this medication whole. Do not break, crush, or chew before swallowing.
• Continue to take Nolvadex even if you feel well. Do not miss any doses. Taking Nolvadex at the same time each day will help you remember to take it.

Nolvadex is an antiestrogen. It works by blocking the action of estrogen on certain tumors. This can prevent the growth of tumors that are driven by estrogen.

If you miss a dose of Nolvadex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Store Nolvadex between 68 and 77 degrees Fahrenheit (20 and 25 degrees C) in tightly closed, light-resistant container. Protect from moisture, heat and light. Do not store in the bathroom. Do not take tablets after the expiry date stated on the label. Keep Nolvadex out of the reach of children and away from pets.

Do not use Nolvadex, if:

• You are allergic to any ingredient in Nolvadex;
• You are using Nolvadex, to reduce the risk of breast cancer and you have a history of blood clots in the lungs or legs;
• You are using Nolvadex, to reduce the risk of breast cancer, and you also take certain anticoagulants (eg warfarin);
• You are taking anastrozole.

• Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Nolvadex may reduce the number of clot forming cells (platelets) in blood. Avoid actions that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
• Nolvadex may lower your body's ability to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection such as fever, sore throat, rash, or chills.
• New tumors have occurred in parts of the body except the uterus in patients taking Nolvadex. While it is unknown if Nolvadex may be the cause. Discuss any questions or concerns with your doctor.
• Women who take Nolvadex, to reduce the risk of breast cancer should have a breast exam, mammogram, and gynecological exam before starting and during treatment with Nolvadex.
• Women who may become pregnant should begin taking Nolvadex during a menstrual period. Women who have irregular menstrual periods should have a pregnancy test immediately prior to Nolvadex. Talk to your doctor if you have any questions about how to begin taking Nolvadex.
• Women who may become pregnant must use effective nonhormonal birth control (eg, condoms, diaphragm) during sexual intercourse while they are taking Nolvadex and for 2 months after they stopped taking the pill. Do not use hormonal contraceptives (eg contraceptive pill), it may not work as well while you are taking Nolvadex. Discuss any questions about effective nonhormonal birth control with your doctor.
• Nolvadex will not prevent you from becoming pregnant.
• Lab tests, including breast exams, mammograms, gynecological exams, complete blood count and liver function, may be performed while you use Nolvadex. These tests can be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Nolvadex should be used with extreme caution in children Safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: Nolvadex may cause harm to the fetus. Do not become pregnant while you are using it and within 2 months after stopping its use. If you think you might be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nolvadex while you are pregnant. It is not known if Nolvadex is found in breast milk. Not to breastfeed, taking Nolvadex.